Comments on: Find Common Ancestors by Comparing Genomes in deCODEme http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/ Your Ancestry, Health and Genetic Testing Sun, 13 Jun 2010 04:34:19 +0000 hourly 1 http://wordpress.org/?v=3.0 By: Reiver http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1461 Reiver Sat, 23 Jan 2010 17:46:03 +0000 http://decodeyou.com/?p=828#comment-1461 How do you determine what is significant though? For example, if I share 0.8% medium at 5Mb with someone, is this saying I share an ancestor with them? If so, how far back roughly? How do you determine what is significant though? For example, if I share 0.8% medium at 5Mb with someone, is this saying I share an ancestor with them? If so, how far back roughly?

]]> By: jim berry http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1451 jim berry Wed, 20 Jan 2010 14:45:18 +0000 http://decodeyou.com/?p=828#comment-1451 You mention instances of medium sharing. How would you interpret the one instance of high sharing on chromosome X? You mention instances of medium sharing. How would you interpret the one instance of high sharing on chromosome X?

]]> By: rogers http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1429 rogers Thu, 14 Jan 2010 22:46:57 +0000 http://decodeyou.com/?p=828#comment-1429 Thanks deCODEme for this new feature. It has certainly made comparisons between friends more informative and interesting. Perhaps one day it might be possible to develop an algorithm to correlate these fragments to time to most recent common ancestor (TMRCA)? Thanks deCODEme for this new feature. It has certainly made comparisons between friends more informative and interesting. Perhaps one day it might be possible to develop an algorithm to correlate these fragments to time to most recent common ancestor (TMRCA)?

]]> By: admin http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1428 admin Thu, 14 Jan 2010 14:10:04 +0000 http://decodeyou.com/?p=828#comment-1428 Thanks for pointing this out Ponto. We have uploaded a new picture and changed the reference to 3Mb. Thanks for pointing this out Ponto. We have uploaded a new picture and changed the reference to 3Mb.

]]> By: Ponto http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1426 Ponto Thu, 14 Jan 2010 07:03:55 +0000 http://decodeyou.com/?p=828#comment-1426 The fragment size of the image is 500Kb, your article says 5Mb. So you are saying that a fragment of 500Kb like the image shows, indicates shared common ancestors from more than 1000 years ago? Ponto. The fragment size of the image is 500Kb, your article says 5Mb. So you are saying that a fragment of 500Kb like the image shows, indicates shared common ancestors from more than 1000 years ago?

Ponto.

]]> By: Davidski http://www.decodeyou.com/find-common-ancestors-by-comparing-genomes-in-decodeme/comment-page-1/#comment-1424 Davidski Thu, 14 Jan 2010 00:11:39 +0000 http://decodeyou.com/?p=828#comment-1424 In fact, even shared segments at 5MB can indicate common ancestors going back many thousands of years, depending on where they're located. That's because some areas are highly conserved. For example, if you show medium sharing in the middle (centromere) of chromosome 11 with a Yakut, Icelander, Bedouin, etc. this probably indicates you shared a common Paleolithic Eurasian ancestor who now has descendants living all the way from Europe to East Asia. In fact, even shared segments at 5MB can indicate common ancestors going back many thousands of years, depending on where they’re located. That’s because some areas are highly conserved. For example, if you show medium sharing in the middle (centromere) of chromosome 11 with a Yakut, Icelander, Bedouin, etc. this probably indicates you shared a common Paleolithic Eurasian ancestor who now has descendants living all the way from Europe to East Asia.

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